Fig. 2. Effect of SST14 pre-treatment on lipotoxicity-induced beta cell apoptosis in primary mouse islet cells. Dispersed mouse islet cells were exposed to 0.5 mmol/l palmitate (PAL) with or without SST14 (100 nmol/l) for 20h following pre-treatment with SST14 for 48h. Apoptosis was measured by counting of DAB-positive cells following TUNEL staining. Data representative of three separate experiments. **P<0.01 vs treatment with palmitate only (one way ANOVA and Bonferroni's multiple comparisons test).